The first root-cause based digital weight loss clinic

Alfie is the first telehealth program designed to treat you through unique medication panels and high touch care to achieve maximum weight loss


A better way to manage obesity.


Creating your Metabolic Profile

We collect your medication history and patient data from a variety of sources to understand your health.
We start with a detailed look into your metabolism with lab testing and other physical metrics.
Lastly, and most fun, we check your gut microbiome health using markers for your poop.

Precision Medication Panels

Meet with a specialist for an in-depth telehealth visit within 48 hours of completing your lab work.
Our doctors prescribe combinations of medications specifically tailored to your biology.
Our doctors update and titrate your medication on a regular basis to maximize your weight loss.

360° Management

We don't just use a one-and-done model, we're in it for the long run, just like you. We'll keep you on track with:

Continuous asynchronous monitoring.
Medication updates and titrations on an ongoing basis.
1:1 Accountability coaching.

By the numbers...

Alfie optimizes weight management through cutting-edge clinical research in our online weight loss clinic.


More effective than habit and lifestyle change alone.


More effective than regularly prescribed medications.


Pounds lost with precision weight management.


Data points analyzed per metabolic profile.

Metabolic weight loss through telehealth

Weight management you can trust

Treament designed by experts in the field

Scott Butsch

Director of Obesity Medicine at the Cleveland Clinic and nicknamed the "father of obesity medicine".

Fatima Stanford

Associate professor at Harvard Medical school and one of the most cited researchers in obesity medicine.

Noreen Reilly Harrington

Assistant Professor of Psychology at Harvard Medical School and an internationally-recognized expert in cognitive-behavioral treatment.

Abeer Bader

Lead Clinical Nutrition Specialist at the Mass General Weight Center, focused on patients struggling with obesity.


Make the change right now

Alfie can help you in the right direction.



At Alfie, we've built precision into weight loss by using research from top weight loss centers

You're unique — your weight loss should be as well.


Frequently Asked Questions

What is Alfie? 

Alfie is the first program to utilize personalized weight loss algorithms to optimize your weight loss through clinically proven science. We utilize intake data from lab results, questionnaires, and physical tests to determine why your body specifically gains weight and through which pathways it will most easily lose weight.

We then take this data to determine which medication, if any, will be most effective to help you lose weight. Based on ongoing data we collect from your connected smart devices and responses to our care team, we update your medication(s) on a biweekly basis to optimize your weight loss if needed.

Who is Alfie for?

We've been in your shoes and are tired of programs that prescribe blanket medications.

Alfie is for anyone over the age of 18 with a BMI of 30 and above or 27 and above with comorbidities such as obstructive sleep apnea, hypertension, dislypidemia, etc. We'll work with you to determine the best combination of medications and coaching to help you lose weight.

To find out if you're eligible, sign up today! 

Are the medications Alfie prescribes safe?

When you sign up for Alfie, you complete a detailed metabolic profile including blood work that is reviewed by your Alfie healthcare professional before prescribing any medication. Alfie providers prescribe a variety of medications that are all approved by the FDA.